7L9I
Crystal structure of human ARH3-D314A bound to magnesium and ADP-ribose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C, D, A, B | ADP-ribose glycohydrolase ARH3 | polymer | 366 | 39234.0 | 4 | UniProt (Q9NX46) Pfam (PF03747) In PDB | Homo sapiens (Human) | ADP-ribosylhydrolase 3,O-acetyl-ADP-ribose deacetylase ARH3,Poly(ADP-ribose) glycohydrolase ARH3,[Protein ADP-ribosylarginine] hydrolase-like protein 2,[Protein ADP-ribosylserine] hydrolase |
| 2 | C, D, A, B | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | non-polymer | 559.3 | 4 | Chemie (AR6) | |||
| 3 | C, D, A, B | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 839 | Chemie (HOH) |
Sequence modifications
C, D, A, B: 1 - 363 (UniProt: Q9NX46)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 314 | Asp 314 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 156935.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2334.5 | |
| All* | Total formula weight | 159270.3 |
