7L72
Crystal structure of the second bromodomain (BD2) of human BRD3 bound to Ro3280
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bromodomain-containing protein 3 | polymer | 113 | 13307.4 | 1 | UniProt (Q15059) Pfam (PF00439) In PDB | Homo sapiens (Human) | RING3-like protein |
2 | A | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | non-polymer | 543.6 | 1 | Chemie (79C) | |||
3 | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
A: 306 - 416 (UniProt: Q15059)
PDB | External Database | Details |
---|---|---|
Ser 304 | - | expression tag |
Met 305 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 13307.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 543.6 | |
All* | Total formula weight | 13851.0 |