7L1T

Crystal structure of human holo SepSecS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	O-phosphoseryl-tRNA(Sec) selenium transferase	polymer	521	57972.6	1	UniProt (Q9HD40) Pfam (PF05889) In PDB	Homo sapiens (Human)	Liver-pancreas antigen,LP,SLA-p35,SLA/LP autoantigen,Selenocysteine synthase,Sec synthase,Selenocysteinyl-tRNA(Sec) synthase,Sep-tRNA:Sec-tRNA synthase,SepSecS,Soluble liver antigen,SLA,UGA suppressor tRNA-associated protein,tRNA(Ser/Sec)-associated antigenic protein
2	A	(5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE	non-polymer		233.2	1	Chemie (PLR)
3	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
4		water	water		18.0	96	Chemie (HOH)

Sequence modifications

A: 1 - 501 (UniProt: Q9HD40)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	57972.6
Non-Polymers*	Number of molecules	2
	Total formula weight	328.1
All*	Total formula weight	58300.7

*Water molecules are not included.