7L1T

Crystal structure of human holo SepSecS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0001514	biological_process	selenocysteine incorporation
A	0001717	biological_process	conversion of seryl-tRNAsec to selenocys-tRNAsec
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0016740	molecular_function	transferase activity
A	0098621	molecular_function	O-phosphoseryl-tRNA(Sec) selenium transferase activity

Functional Information from PROSITE/UniProt

site_id	PS00435
Number of Residues	11
Details	PEROXIDASE_1 Peroxidases proximal heme-ligand signature. DIIKLAGVHTV

Chain	Residue	Details
A	ASP124-VAL134

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Region: {"description":"Phosphate loop (P-loop)","evidences":[{"source":"PubMed","id":"19608919","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19608919","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"May act as a substrate filter by repelling compounds with a negatively charged alpha-carboxylate","evidences":[{"source":"UniProtKB","id":"Q6P6M7","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"19608919","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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