7L0G
Monobody 12VC1 Bound to HRAS(G12C)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, G (A, B, E, G) | GTPase HRas | polymer | 167 | 19008.4 | 4 | UniProt (P01112) Pfam (PF00071) | Homo sapiens (Human) | H-Ras-1,Ha-Ras,Transforming protein p21,c-H-ras,p21ras |
| 2 | C, D, F, H (C, D, F, H) | Monobody 12VC1 | polymer | 97 | 10229.6 | 4 | Homo sapiens | ||
| 3 | I, K, M, O (A, B, E, G) | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | non-polymer | 539.2 | 4 | Chemie (GSP) | |||
| 4 | J, L, N, P (A, B, E, G) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A, B, E, G: 1 - 166 (UniProt: P01112)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Cys 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 116951.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2254.2 | |
| All* | Total formula weight | 119206.0 |
