7KX8
Crystal structure of DCLK1-Cter in complex with FMF-03-055-1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Serine/threonine-protein kinase DCLK1 | polymer | 317 | 35101.0 | 2 | UniProt (O15075) Pfam (PF00069) In PDB | Homo sapiens (Human) | Doublecortin domain-containing protein 3A,Doublecortin-like and CAM kinase-like 1,Doublecortin-like kinase 1 |
2 | A, B | 5-ethyl-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one | non-polymer | 473.6 | 2 | Chemie (X8J) |
Sequence modifications
A, B: 372 - 687 (UniProt: O15075)
PDB | External Database | Details |
---|---|---|
Gly 370 | - | expression tag |
Ser 371 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 70202.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 947.1 | |
All* | Total formula weight | 71149.1 |