7KX6
Crystal structure of DCLK1-KD in complex with XMD8-85
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Serine/threonine-protein kinase DCLK1 | polymer | 280 | 31299.7 | 2 | UniProt (O15075) Pfam (PF00069) In PDB | Homo sapiens (Human) | Doublecortin domain-containing protein 3A,Doublecortin-like and CAM kinase-like 1,Doublecortin-like kinase 1 |
| 2 | A, B | 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one | non-polymer | 459.5 | 2 | Chemie (X7Y) | |||
| 3 | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A, B: 372 - 649 (UniProt: O15075)
| PDB | External Database | Details |
|---|---|---|
| Gly 370 | - | expression tag |
| Ser 371 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62599.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 919.1 | |
| All* | Total formula weight | 63518.6 |
