7KX1

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, Y110F mutant with pyruvate bound in the active in C2221 space group

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34169.3	6	UniProt (Q9PPB4) Pfam (PF00701) In PDB	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	HTPA synthase
2	A, B, C, D, E...	TRIETHYLENE GLYCOL	non-polymer		150.2	6	Chemie (PGE)
3	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	B, C, D, F	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
5	B, C, E, F	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
6	C	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
7		water	water		18.0	601	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Phe 110	Tyr 110	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	205015.5
Non-Polymers*	Number of molecules	18
	Total formula weight	1602.3
All*	Total formula weight	206617.8

*Water molecules are not included.