7KUF

Transcription activation subcomplex with WhiB7 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Probable transcriptional regulator WhiB7	polymer	92	10153.8	1	UniProt (Q6MX01) Pfam (PF02467) Pfam (PF02178)	Mycobacterium tuberculosis
2	B (B)	RNA polymerase sigma factor, DNA-directed RNA polymerase subunit beta chimera	polymer	112	12650.2	1	UniProt (A0A654TMB9) UniProt (A1KGE7) Pfam (PF04545) UniProt (by SIFTS) (P9WGI1) UniProt (by SIFTS) (P9WGY9)	Mycobacterium tuberculosis	RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3	C (C)	DNA (5'-D(*CP*AP*GP*AP*AP*AP*AP*TP*CP*GP*GP*TP*TP*GP*TP*GP*GP*T)-3')	polymer	18	5595.6	1		Mycobacterium tuberculosis
4	D (D)	DNA (5'-D(*GP*AP*CP*CP*AP*CP*AP*AP*CP*CP*GP*AP*TP*TP*TP*TP*CP*T)-3')	polymer	18	5435.5	1		Mycobacterium tuberculosis
5	E (A)	IRON/SULFUR CLUSTER	non-polymer		351.6	1	Chemie (SF4)

Sequence modifications

B: 446 - 528 (UniProt: A0A654TMB9)

PDB	External Database	Details
Met 438	-	initiating methionine
Ala 439	-	expression tag
His 440	-	expression tag
His 441	-	expression tag
His 442	-	expression tag
His 443	-	expression tag
His 444	-	expression tag
His 445	-	expression tag
Gly 529	-	linker
Ser 530	-	linker
Ser 531	-	linker
Gly 532	-	linker
Ser 533	-	linker
Gly 534	-	linker

B: 535 - 549 (UniProt: A1KGE7)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	33835.2
Non-Polymers*	Number of molecules	1
	Total formula weight	351.6
All*	Total formula weight	34186.9

*Water molecules are not included.