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7KTS

Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein,Transformation/transcription domain-associated proteinpolymer3848419168.11UniProt (F2Z2U4)
Pfam (PF20175)
Pfam (PF20206)
Pfam (PF02259)
Pfam (PF00454)
Homo sapiens (Human)
2B
(B)
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5Lpolymer58966223.01UniProt (O75529)
Pfam (PF00400)
Pfam (PF04494)
Homo sapiens (Human)TAF5L,PCAF-associated factor 65 beta,PAF65-beta
3C
(C)
Isoform 3 of Transcription factor SPT20 homologpolymer81188129.11UniProt (Q8NEM7)
Pfam (PF12090)
Homo sapiens (Human)p38-interacting protein,p38IP
4D
(D)
STAGA complex 65 subunit gamma, DhaA,STAGA complex 65 subunit gamma,STAGA complex 65 subunit gamma, DhaA,STAGA complex 65 subunit gamma,STAGA complex 65 subunit gamma, DhaApolymer74983013.71UniProt (O94864)
Pfam (PF07524)
Homo sapiensAdenocarcinoma antigen ART1,SPTF-associated factor 65 gamma,STAF65gamma,Suppressor of Ty 7-like,Adenocarcinoma antigen ART1,SPTF-associated factor 65 gamma,STAF65gamma,Suppressor of Ty 7-like
5E
(E)
Transcription initiation factor TFIID subunit 9Bpolymer25127654.91UniProt (Q9HBM6)
Pfam (PF02291)
Homo sapiens (Human)Neuronal cell death-related protein 7,DN-7,Transcription initiation factor TFIID subunit 9-like,Transcription-associated factor TAFII31L
6F
(F)
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L,TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L,TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6Lpolymer62262027.71UniProt (Q9Y6J9)
Pfam (PF02969)
Pfam (PF07571)
Homo sapiens (Human)TAF6L,PCAF-associated factor 65-alpha,PAF65-alpha,TAF6L,PCAF-associated factor 65-alpha,PAF65-alpha
7G
(G)
Transcription initiation factor TFIID subunit 12polymer16117948.51UniProt (Q16514)
Pfam (PF03847)
Homo sapiens (Human)Transcription initiation factor TFIID 20/15 kDa subunits,TAFII20/TAFII15
8H
(H)
Transcription initiation factor TFIID subunit 10polymer21821731.21UniProt (Q12962)
Pfam (PF03540)
Homo sapiens (Human)STAF28,Transcription initiation factor TFIID 30 kDa subunit,TAFII30
9I
(I)
Transcription initiation protein SPT3 homolog,Transcription initiation protein SPT3 homolog,Transcription initiation protein SPT3 homologpolymer31735447.51UniProt (O75486)
Pfam (PF02269)
Homo sapiens (Human)SPT3-like protein,SPT3-like protein
10J
(J)
Transcriptional adapter 1polymer33537432.51UniProt (Q96BN2)
Pfam (PF12767)
Homo sapiens (Human)SPT3-associated factor 42,STAF42,Transcriptional adapter 1-like protein
11K
(N)
Ataxin-7polymer89295597.71UniProt (O15265)
Pfam (PF08313)
Homo sapiens (Human)Spinocerebellar ataxia type 7 protein
12L
(S)
Splicing factor 3B subunit 3polymer1217135718.81UniProt (Q15393)
Pfam (PF10433)
Pfam (PF03178)
Homo sapiens (Human)Pre-mRNA-splicing factor SF3b 130 kDa subunit,SF3b130,STAF130,Spliceosome-associated protein 130,SAP 130
13M
(T)
Splicing factor 3B subunit 5polymer8610149.41UniProt (Q9BWJ5)
Pfam (PF07189)
Homo sapiens (Human)SF3b5,Pre-mRNA-splicing factor SF3b 10 kDa subunit
Sequence modifications
A: -10 - 329 (UniProt: F2Z2U4)
A: 330 - 357 (PDB: 7KTS)
A: 358 - 1677 (UniProt: F2Z2U4)
A: 1678 - 2288 (PDB: 7KTS)
A: 2289 - 3837 (UniProt: F2Z2U4)
D: -3 - 47 (PDB: 7KTS)
D: 52 - 87 (UniProt: O94864)
D: 87 - 117 (PDB: 7KTS)
D: 119 - 414 (UniProt: O94864)
D: 415 - 749 (PDB: 7KTS)
F: 1 - 134 (UniProt: Q9Y6J9)
F: 135 - 374 (PDB: 7KTS)
F: 375 - 622 (UniProt: Q9Y6J9)
I: 1 - 156 (UniProt: O75486)
I: 157 - 186 (PDB: 7KTS)
I: 187 - 317 (UniProt: O75486)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains13
Total formula weight1100242.1
All*Total formula weight1100242.1
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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