7KTS
Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein | polymer | 3848 | 419168.1 | 1 | UniProt (F2Z2U4) Pfam (PF20175) Pfam (PF20206) Pfam (PF02259) Pfam (PF00454) In PDB | Homo sapiens (Human) | |
| 2 | B | TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L | polymer | 589 | 66223.0 | 1 | UniProt (O75529) Pfam (PF00400) Pfam (PF04494) In PDB | Homo sapiens (Human) | TAF5L,PCAF-associated factor 65 beta,PAF65-beta |
| 3 | C | Isoform 3 of Transcription factor SPT20 homolog | polymer | 811 | 88129.1 | 1 | UniProt (Q8NEM7) Pfam (PF12090) In PDB | Homo sapiens (Human) | p38-interacting protein,p38IP |
| 4 | D | STAGA complex 65 subunit gamma, DhaA,STAGA complex 65 subunit gamma,STAGA complex 65 subunit gamma, DhaA,STAGA complex 65 subunit gamma,STAGA complex 65 subunit gamma, DhaA | polymer | 749 | 83013.7 | 1 | UniProt (O94864) Pfam (PF07524) In PDB | Homo sapiens | Adenocarcinoma antigen ART1,SPTF-associated factor 65 gamma,STAF65gamma,Suppressor of Ty 7-like,Adenocarcinoma antigen ART1,SPTF-associated factor 65 gamma,STAF65gamma,Suppressor of Ty 7-like |
| 5 | E | Transcription initiation factor TFIID subunit 9B | polymer | 251 | 27654.9 | 1 | UniProt (Q9HBM6) Pfam (PF02291) In PDB | Homo sapiens (Human) | Neuronal cell death-related protein 7,DN-7,Transcription initiation factor TFIID subunit 9-like,Transcription-associated factor TAFII31L |
| 6 | F | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L,TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L,TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L | polymer | 622 | 62027.7 | 1 | UniProt (Q9Y6J9) Pfam (PF02969) Pfam (PF07571) In PDB | Homo sapiens (Human) | TAF6L,PCAF-associated factor 65-alpha,PAF65-alpha,TAF6L,PCAF-associated factor 65-alpha,PAF65-alpha |
| 7 | G | Transcription initiation factor TFIID subunit 12 | polymer | 161 | 17948.5 | 1 | UniProt (Q16514) Pfam (PF03847) In PDB | Homo sapiens (Human) | Transcription initiation factor TFIID 20/15 kDa subunits,TAFII20/TAFII15 |
| 8 | H | Transcription initiation factor TFIID subunit 10 | polymer | 218 | 21731.2 | 1 | UniProt (Q12962) Pfam (PF03540) In PDB | Homo sapiens (Human) | STAF28,Transcription initiation factor TFIID 30 kDa subunit,TAFII30 |
| 9 | I | Transcription initiation protein SPT3 homolog,Transcription initiation protein SPT3 homolog,Transcription initiation protein SPT3 homolog | polymer | 317 | 35447.5 | 1 | UniProt (O75486) Pfam (PF02269) In PDB | Homo sapiens (Human) | SPT3-like protein,SPT3-like protein |
| 10 | J | Transcriptional adapter 1 | polymer | 335 | 37432.5 | 1 | UniProt (Q96BN2) Pfam (PF12767) In PDB | Homo sapiens (Human) | SPT3-associated factor 42,STAF42,Transcriptional adapter 1-like protein |
| 11 | N | Ataxin-7 | polymer | 892 | 95597.7 | 1 | UniProt (O15265) Pfam (PF08313) In PDB | Homo sapiens (Human) | Spinocerebellar ataxia type 7 protein |
| 12 | S | Splicing factor 3B subunit 3 | polymer | 1217 | 135718.8 | 1 | UniProt (Q15393) Pfam (PF10433) Pfam (PF03178) In PDB | Homo sapiens (Human) | Pre-mRNA-splicing factor SF3b 130 kDa subunit,SF3b130,STAF130,Spliceosome-associated protein 130,SAP 130 |
| 13 | T | Splicing factor 3B subunit 5 | polymer | 86 | 10149.4 | 1 | UniProt (Q9BWJ5) Pfam (PF07189) In PDB | Homo sapiens (Human) | SF3b5,Pre-mRNA-splicing factor SF3b 10 kDa subunit |
Sequence modifications
A: -10 - 329 (UniProt: F2Z2U4)
A: 330 - 357 (PDB: 7KTS)
A: 358 - 1677 (UniProt: F2Z2U4)
A: 1678 - 2288 (PDB: 7KTS)
A: 2289 - 3837 (UniProt: F2Z2U4)
D: -3 - 47 (PDB: 7KTS)
D: 52 - 87 (UniProt: O94864)
D: 87 - 117 (PDB: 7KTS)
D: 119 - 414 (UniProt: O94864)
D: 415 - 749 (PDB: 7KTS)
F: 1 - 134 (UniProt: Q9Y6J9)
F: 135 - 374 (PDB: 7KTS)
F: 375 - 622 (UniProt: Q9Y6J9)
I: 1 - 156 (UniProt: O75486)
I: 157 - 186 (PDB: 7KTS)
I: 187 - 317 (UniProt: O75486)
A: 330 - 357 (PDB: 7KTS)
A: 358 - 1677 (UniProt: F2Z2U4)
A: 1678 - 2288 (PDB: 7KTS)
A: 2289 - 3837 (UniProt: F2Z2U4)
D: -3 - 47 (PDB: 7KTS)
D: 52 - 87 (UniProt: O94864)
D: 87 - 117 (PDB: 7KTS)
D: 119 - 414 (UniProt: O94864)
D: 415 - 749 (PDB: 7KTS)
F: 1 - 134 (UniProt: Q9Y6J9)
F: 135 - 374 (PDB: 7KTS)
F: 375 - 622 (UniProt: Q9Y6J9)
I: 1 - 156 (UniProt: O75486)
I: 157 - 186 (PDB: 7KTS)
I: 187 - 317 (UniProt: O75486)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 13 |
| Total formula weight | 1100242.1 | |
| All* | Total formula weight | 1100242.1 |
