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7KTE

DNA Polymerase Mu, 8-oxodGTP:Ct Reaction State Ternary Complex, 50 mM Mg2+ (90min)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA-directed DNA/RNA polymerase mupolymer35640054.41UniProt (Q9NP87)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
In PDB
Homo sapiens (Human)Pol Mu,Terminal transferase
2TDNA (5'-D(*CP*GP*GP*CP*CP*TP*AP*CP*G)-3')polymer92716.81Homo sapiens
3PDNA (5'-D(*CP*GP*TP*AP*(8OG))-3')polymer51536.01Homo sapiens
4DDNA (5'-D(P*GP*CP*CP*G)-3')polymer41191.81Homo sapiens
5AMAGNESIUM IONnon-polymer24.32Chemie (MG)
6ASODIUM IONnon-polymer23.01Chemie (NA)
7ACHLORIDE IONnon-polymer35.51Chemie (CL)
8APYROPHOSPHATEnon-polymer178.01Chemie (PPV)
9A8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (8DG)
10A, P1,2-ETHANEDIOLnon-polymer62.17Chemie (EDO)
11A4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
12A2,3-DIHYDROXY-1,4-DITHIOBUTANEnon-polymer154.31Chemie (DTT)
13TGLYCEROLnon-polymer92.11Chemie (GOL)
14waterwater18.0450Chemie (HOH)
Sequence modifications
A: 132 - 494 (UniProt: Q9NP87)
PDBExternal DatabaseDetails
Gly 127-expression tag
Ser 128-expression tag
Ala 129-expression tag
Ala 130-expression tag
Ala 131-expression tag
Gly 410Pro 398linker
-Gly 399deletion
-Ala 400deletion
-Ala 401deletion
-Val 402deletion
-Gly 403deletion
-Gly 404deletion
-Ser 405deletion
-Thr 406deletion
-Arg 407deletion
-Pro 408deletion
-Cys 409deletion
-Pro 410deletion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight45499.1
Non-Polymers*Number of molecules16
Total formula weight1727.3
All*Total formula weight47226.4
*Water molecules are not included.

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PDB entries from 2024-06-12

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