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7KSU

DNA Polymerase Mu, dGTP:Ct Product State Ternary Complex, 10 mM Mn2+ (4min)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed DNA/RNA polymerase mupolymer35640054.41UniProt (Q9NP87)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)Pol Mu,Terminal transferase
2B
(T)
DNA (5'-D(*CP*GP*GP*CP*CP*TP*AP*CP*G)-3')polymer92716.81Homo sapiens
3C
(P)
DNA (5'-D(*CP*GP*TP*AP*G)-3')polymer51520.01Homo sapiens
4D
(D)
DNA (5'-D(P*GP*CP*CP*G)-3')polymer41191.81Homo sapiens
5E, F, G, H, I...
(A, T, P)
MANGANESE (II) IONnon-polymer54.97Chemie (MN)
6J
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
7K
(A)
PYROPHOSPHATEnon-polymer178.01Chemie (PPV)
8L, M, N, O, P
(A)
1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
9Q
(A)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
10R
(A)
2,3-DIHYDROXY-1,4-DITHIOBUTANEnon-polymer154.31Chemie (DTT)
11U, V, W, X
(A, T, P, D)
waterwater18.0298Chemie (HOH)
Sequence modifications
A: 127 - 494 (UniProt: Q9NP87)
PDBExternal DatabaseDetails
Ser 128Pro 128conflict
Ala 129Arg 129conflict
Ala 130Lys 130conflict
Ala 131Gly 131conflict
-Pro 398deletion
-Gly 399deletion
-Ala 400deletion
-Ala 401deletion
-Val 402deletion
-Gly 403deletion
-Gly 404deletion
-Ser 405deletion
-Thr 406deletion
-Arg 407deletion
-Pro 408deletion
-Cys 409deletion
Gly 410Pro 410conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight45483.1
Non-Polymers*Number of molecules16
Total formula weight1288.4
All*Total formula weight46771.5
*Water molecules are not included.

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PDB entries from 2025-12-03

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