7KQX
MIF Y99C homotrimeric mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Macrophage migration inhibitory factor | polymer | 114 | 12295.0 | 3 | UniProt (P14174) Pfam (PF01187) In PDB | Homo sapiens (Human) | MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase |
| 2 | A, B, C | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | A, B, C | GLYCEROL | non-polymer | 92.1 | 15 | Chemie (GOL) | |||
| 4 | A, B | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 5 | Chemie (IPA) | |||
| 5 | water | water | 18.0 | 365 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 114 (UniProt: P14174)
| PDB | External Database | Details |
|---|---|---|
| Cys 99 | Tyr 100 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 36885.1 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 1970.1 | |
| All* | Total formula weight | 38855.1 |
