7KPA
asymmetric hTNF-alpha
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Tumor necrosis factor | polymer | 158 | 17457.7 | 3 | UniProt (P01375) Pfam (PF00229) In PDB | Homo sapiens (Human) | Cachectin,TNF-alpha,Tumor necrosis factor ligand superfamily member 2,TNF-a |
| 2 | C | 5-(1-{[2-(difluoromethoxy)phenyl]methyl}-2-{[3-(2-oxopyrrolidin-1-yl)phenoxy]methyl}-1H-benzimidazol-6-yl)pyridin-2(1H)-one | non-polymer | 556.6 | 1 | Chemie (D84) | |||
| 3 | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 157 (UniProt: P01375)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 52373.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 556.6 | |
| All* | Total formula weight | 52929.8 |
