7KP4

Crystal structure of human claudin-4 in complex with Clostridium perfringens enterotoxin C-terminal domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Claudin-4	polymer	214	22613.9	1	UniProt (O14493) Pfam (PF00822) In PDB	Homo sapiens (Human)	Clostridium perfringens enterotoxin receptor,CPE-receptor,Williams-Beuren syndrome chromosomal region 8 protein
2	B	Heat-labile enterotoxin B chain	polymer	134	15114.9	1	UniProt (P01558) In PDB	Clostridium perfringens

Sequence modifications

A: 1 - 209 (UniProt: O14493)

PDB	External Database	Details
Gly 210	-	expression tag
Leu 211	-	expression tag
Val 212	-	expression tag
Pro 213	-	expression tag
Arg 214	-	expression tag

B: 192 - 319 (UniProt: P01558)

PDB	External Database	Details
Met 191	-	initiating methionine
Gly 320	-	expression tag
Leu 321	-	expression tag
Val 322	-	expression tag
Pro 323	-	expression tag
Arg 324	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	37728.8
All*	Total formula weight	37728.8

*Water molecules are not included.