7KO1

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, E88D mutant with pyruvate bound in the active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34171.2	6	UniProt (Q9PPB4) Pfam (PF00701)	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	HTPA synthase
2	G, H, I, K, P... (A, B, C, E, F)	MAGNESIUM ION	non-polymer		24.3	9	Chemie (MG)
3	J, L, R, S, V (A, B, C, D, E)	TRIETHYLENE GLYCOL	non-polymer		150.2	5	Chemie (PGE)
4	BA, M, N, T, W... (F, B, D, E)	ACETATE ION	non-polymer		59.0	6	Chemie (ACT)
5	CA, O (F, B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6	AA (F)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
7	DA, EA, FA, GA, HA... (A, B, C, D, E...)	water	water		18.0	561	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Asp 88	Glu 88	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	205027.4
Non-Polymers*	Number of molecules	23
	Total formula weight	1554.1
All*	Total formula weight	206581.5

*Water molecules are not included.