7KMG

LY-CoV555 neutralizing antibody against SARS-CoV-2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	LY-CoV555 Fab heavy chain	polymer	229	24807.8	2		Homo sapiens
2	B, E	LY-CoV555 Fab light chain	polymer	212	23097.6	2		Homo sapiens
3	C, F	Spike protein S1	polymer	205	23173.9	2	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2 COVID-19 virus)	S glycoprotein,E2,Peplomer protein,Spike glycoprotein
4	A, E	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5		water	water		18.0	197	Chemie (HOH)

Sequence modifications

C, F: 329 - 527 (UniProt: P0DTC2)

PDB	External Database	Details
His 528	-	expression tag
His 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	142158.6
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	142342.8

*Water molecules are not included.