7KK1

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, N84A mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34142.2	6	UniProt (Q9PPB4) Pfam (PF00701)	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	HTPA synthase
2	CB, G, IA, LB, R... (E, A, C, F, B...)	LYSINE	non-polymer		147.2	6	Chemie (LYS)
3	DB, EB, H, I, JA... (E, A, C, F, B...)	MAGNESIUM ION	non-polymer		24.3	15	Chemie (MG)
4	AA, BA, CA, DA, FB... (B, E, A, C, F...)	1,2-ETHANEDIOL	non-polymer		62.1	26	Chemie (EDO)
5	BB, HA, IB, P, RA... (D, B, E, A, C...)	TRIETHYLENE GLYCOL	non-polymer		150.2	6	Chemie (PGE)
6	JB, Q, SA (E, A, C)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	3	Chemie (PEG)
7	AB, EA, FA, GA, HB... (D, B, E, C, F)	ACETATE ION	non-polymer		59.0	10	Chemie (ACT)
8	KB (E)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
9	AC, VB, WB, XB, YB... (F, A, B, C, D...)	water	water		18.0	1184	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 84	Asn 84	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	204853.4
Non-Polymers*	Number of molecules	67
	Total formula weight	4763.4
All*	Total formula weight	209616.8

*Water molecules are not included.