7KHM

Crystal structure of hDHHS20 bound to palmitoyl CoA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Isoform 4 of Palmitoyltransferase ZDHHC20	polymer	330	38494.3	2	UniProt (Q5W0Z9) Pfam (PF01529) In PDB	Homo sapiens (Human)	Acyltransferase ZDHHC20,DHHC domain-containing cysteine-rich protein 20,DHHC20,Zinc finger DHHC domain-containing protein 20
2	A, B	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	A, B	Palmitoyl-CoA	non-polymer		1005.9	2	Chemie (PKZ)
4	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5		water	water		18.0	14	Chemie (HOH)

Sequence modifications

A, B: 2 - 320 (UniProt: Q5W0Z9)

PDB	External Database	Details
Gly -6	-	expression tag
Pro -5	-	expression tag
Ser -4	-	expression tag
Arg -3	-	expression tag
Ala -2	-	expression tag
Thr -1	-	expression tag
Met 0	-	expression tag
Gly 1	-	expression tag
Ser 156	Cys 156	engineered mutation
Ser 321	-	expression tag
Asn 322	-	expression tag
Ser 323	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76988.6
Non-Polymers*	Number of molecules	7
	Total formula weight	2368.5
All*	Total formula weight	79357.1

*Water molecules are not included.