7KHM
Crystal structure of hDHHS20 bound to palmitoyl CoA
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 166 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"29326245","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 66 |
| Details | Topological domain: {"description":"Lumenal","evidences":[{"source":"PubMed","id":"29326245","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 188 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"29326245","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 100 |
| Details | Domain: {"description":"DHHC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00067","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Active site: {"description":"S-palmitoyl cysteine intermediate","evidences":[{"source":"PubMed","id":"29326245","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29326245","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6BMN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29326245","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important for selectivity toward medium-length fatty acids","evidences":[{"source":"PubMed","id":"29326245","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
