7KHM
Crystal structure of hDHHS20 bound to palmitoyl CoA
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 166 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:29326245 |
| Chain | Residue | Details |
| A | GLY15-VAL35 | |
| A | TYR54-PHE74 | |
| A | PHE170-LEU190 | |
| A | PHE208-HIS231 | |
| B | GLY15-VAL35 | |
| B | TYR54-PHE74 | |
| B | PHE170-LEU190 | |
| B | PHE208-HIS231 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 66 |
| Details | TOPO_DOM: Lumenal => ECO:0000269|PubMed:29326245 |
| Chain | Residue | Details |
| A | GLU36-VAL53 | |
| A | GLU191-LYS207 | |
| B | GLU36-VAL53 | |
| B | GLU191-LYS207 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 188 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:29326245 |
| Chain | Residue | Details |
| A | THR75-LYS169 | |
| B | THR75-LYS169 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | ACT_SITE: S-palmitoyl cysteine intermediate => ECO:0000269|PubMed:29326245 |
| Chain | Residue | Details |
| A | SER156 | |
| B | SER156 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29326245, ECO:0007744|PDB:6BMN |
| Chain | Residue | Details |
| A | CYS128 | |
| B | CYS131 | |
| B | HIS141 | |
| B | CYS142 | |
| B | CYS145 | |
| B | CYS148 | |
| B | HIS155 | |
| B | CYS162 | |
| A | CYS131 | |
| A | HIS141 | |
| A | CYS142 | |
| A | CYS145 | |
| A | CYS148 | |
| A | HIS155 | |
| A | CYS162 | |
| B | CYS128 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:29326245 |
| Chain | Residue | Details |
| A | LYS135 | |
| A | HIS140 | |
| B | LYS135 | |
| B | HIS140 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | SITE: Important for selectivity toward medium-length fatty acids => ECO:0000269|PubMed:29326245 |
| Chain | Residue | Details |
| A | SER29 | |
| A | TYR181 | |
| B | SER29 | |
| B | TYR181 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER305 | |
| B | SER305 |
