7KHG
Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX3397
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mast/stem cell growth factor receptor Kit | polymer | 335 | 38042.1 | 1 | Pfam (PF07714) UniProt (by SIFTS) (P10721) | Homo sapiens (human) | |
| 2 | B (A) | 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine | non-polymer | 417.8 | 1 | Chemie (P31) | |||
| 3 | C (A) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38042.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 417.8 | |
| All* | Total formula weight | 38459.9 |
