7KH9
Crystal structure of OXA-48 K73A in complex with imipenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Beta-lactamase | polymer | 244 | 28193.9 | 2 | UniProt (Q6XEC0) Pfam (PF00905) | Klebsiella pneumoniae | Oxacillinase-48, OXA-48 beta-lactamase |
| 2 | C, F (B, A) | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid | non-polymer | 301.4 | 2 | Chemie (IM2) | |||
| 3 | D, E, G, H (B, A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | I, J (B, A) | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
B, A: 25 - 265 (UniProt: Q6XEC0)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| His 23 | - | expression tag |
| Met 24 | - | expression tag |
| Ala 73 | Lys 73 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56387.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 744.5 | |
| All* | Total formula weight | 57132.4 |
