7KH9
Crystal structure of OXA-48 K73A in complex with imipenem
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Beta-lactamase | polymer | 244 | 28193.9 | 2 | UniProt (Q6XEC0) Pfam (PF00905) In PDB | Klebsiella pneumoniae | Oxacillinase-48, OXA-48 beta-lactamase |
2 | B, A | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid | non-polymer | 301.4 | 2 | Chemie (IM2) | |||
3 | B, A | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
4 | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
B, A: 25 - 265 (UniProt: Q6XEC0)
PDB | External Database | Details |
---|---|---|
Gly 22 | - | expression tag |
His 23 | - | expression tag |
Met 24 | - | expression tag |
Ala 73 | Lys 73 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 56387.9 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 744.5 | |
All* | Total formula weight | 57132.4 |