7KH9

Crystal structure of OXA-48 K73A in complex with imipenem

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008658	molecular_function	penicillin binding
A	0008800	molecular_function	beta-lactamase activity
A	0016787	molecular_function	hydrolase activity
A	0046677	biological_process	response to antibiotic
A	0071555	biological_process	cell wall organization
B	0005886	cellular_component	plasma membrane
B	0008658	molecular_function	penicillin binding
B	0008800	molecular_function	beta-lactamase activity
B	0016787	molecular_function	hydrolase activity
B	0046677	biological_process	response to antibiotic
B	0071555	biological_process	cell wall organization

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Acyl-ester intermediate => ECO:0000255|PIRSR:PIRSR602137-50, ECO:0000269|PubMed:25406838, ECO:0000269|PubMed:26731698, ECO:0000269|PubMed:31358584, ECO:0000269|PubMed:32150407, ECO:0007744|PDB:4WMC, ECO:0007744|PDB:5FAQ, ECO:0007744|PDB:5FAS, ECO:0007744|PDB:6P97, ECO:0007744|PDB:6P98, ECO:0007744|PDB:6P99, ECO:0007744|PDB:6P9C, ECO:0007744|PDB:6V1O

Chain	Residue	Details
B	SER70
A	SER70

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q8RLA6

Chain	Residue	Details
B	SER70
B	SER118
B	ARG250
A	SER70
A	SER118
A	ARG250

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P13661

Chain	Residue	Details
B	ALA73
A	ALA73

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site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: N6-carboxylysine => ECO:0000255|PIRSR:PIRSR602137-50, ECO:0000269|PubMed:19477418, ECO:0000269|PubMed:25406838, ECO:0007744|PDB:3HBR, ECO:0007744|PDB:4WMC

Chain	Residue	Details
B	ALA73
A	ALA73

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