7KGU
Structure of 2Q1-Fab, an antibody selective for IDH2R140Q-HLA-B*07:02
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, H (A, C, E, L) | Light Chain, Fab fragment, IGG | polymer | 214 | 23449.0 | 4 | Homo sapiens (human) | ||
| 2 | B, D, F, G (B, D, F, H) | Heavy Chain, Fab, IGG, Fab | polymer | 218 | 23308.1 | 4 | Homo sapiens (human) | ||
| 3 | AA, AB, BA, I, KA... (D, L, A, F, H...) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 7 | Chemie (PEG) | |||
| 4 | J (A) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) | |||
| 5 | BB, CA, DA, EA, FA... (L, D, A, F, B...) | SULFATE ION | non-polymer | 96.1 | 33 | Chemie (SO4) | |||
| 6 | O, P (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 7 | CB, RA (L, F) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 8 | YA (H) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 9 | ZA (L) | GLYCINE | non-polymer | 75.1 | 1 | Chemie (GLY) | |||
| 10 | DB, EB, FB, GB, HB... (A, B, C, D, E...) | water | water | 18.0 | 595 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 187028.5 | |
| Non-Polymers* | Number of molecules | 47 |
| Total formula weight | 4695.7 | |
| All* | Total formula weight | 191724.2 |
