7KEJ

BDBV-289 bound to EBOV GPdMuc Makona

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, C, A	Virion spike glycoprotein	polymer	313	34978.6	3	UniProt (A0A1C4HDV6) Pfam (PF01611) UniProt (by SIFTS) (Q05320) In PDB	Ebola virus
2	H, I, G	Antibody Fab heavy chain (HC) BDBV-289	polymer	251	26864.3	3		Homo sapiens
3	K, L, J	Antibody Fab light chain (LC) BDBV-289	polymer	231	24725.4	3		Homo sapiens
4	E, F, D	Virion spike glycoprotein	polymer	203	22158.6	3	UniProt (A0A0E3XK95) Pfam (PF22307) UniProt (by SIFTS) (Q05320) In PDB	Zaire ebolavirus
5	M, N, O	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	3	In PDB GlyTouCan (G22768VO)
6	B, C, A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	9	Chemie (NAG)

Sequence modifications

B, C, A: 32 - 309 (UniProt: A0A1C4HDV6)

PDB	External Database	Details
Met -3	-	expression tag
Asp -2	-	expression tag
Ala -1	-	expression tag
Met 0	-	expression tag
Lys 1	-	expression tag
Arg 2	-	expression tag
Gly 3	-	expression tag
Leu 4	-	expression tag
Cys 5	-	expression tag
Cys 6	-	expression tag
Val 7	-	expression tag
Leu 8	-	expression tag
Leu 9	-	expression tag
Leu 10	-	expression tag
Cys 11	-	expression tag
Gly 12	-	expression tag
Ala 13	-	expression tag
Val 14	-	expression tag
Phe 15	-	expression tag
Val 16	-	expression tag
Ser 17	-	expression tag
Pro 18	-	expression tag
Ser 19	-	expression tag
Gln 20	-	expression tag
Glu 21	-	expression tag
Ile 22	-	expression tag
His 23	-	expression tag
Ala 24	-	expression tag
Arg 25	-	expression tag
Phe 26	-	expression tag
Arg 27	-	expression tag
Arg 28	-	expression tag
Gly 29	-	expression tag
Ala 30	-	expression tag
Arg 31	-	expression tag

E, F, D: 461 - 633 (UniProt: A0A0E3XK95)

PDB	External Database	Details
Asp 630	Phe 630	conflict
Asp 631	Val 631	conflict
Ala 634	-	expression tag
Gly 635	-	expression tag
Trp 636	-	expression tag
Ser 637	-	expression tag
His 638	-	expression tag
Pro 639	-	expression tag
Gln 640	-	expression tag
Phe 641	-	expression tag
Glu 642	-	expression tag
Lys 643	-	expression tag
Gly 644	-	expression tag
Gly 645	-	expression tag
Gly 646	-	expression tag
Ser 647	-	expression tag
Gly 648	-	expression tag
Gly 649	-	expression tag
Gly 650	-	expression tag
Ser 651	-	expression tag
Gly 652	-	expression tag
Gly 653	-	expression tag
Gly 654	-	expression tag
Ser 655	-	expression tag
Trp 656	-	expression tag
Ser 657	-	expression tag
His 658	-	expression tag
Pro 659	-	expression tag
Gln 660	-	expression tag
Phe 661	-	expression tag
Glu 662	-	expression tag
Lys 663	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	326180.8
Branched	Number of molecules	3
	Total formula weight	2732.5
Non-Polymers*	Number of molecules	9
	Total formula weight	1990.9
All*	Total formula weight	330904.2

*Water molecules are not included.