7KCX
Crystal structure of S. aureus penicillin-binding protein 4 (PBP4) mutant (R200L) in complex with cefoxitin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Penicillin-binding protein 4 | polymer | 367 | 41054.3 | 1 | UniProt (A0A0H2WY27) Pfam (PF00144) Pfam (PF00768) Pfam (PF09211) In PDB | Staphylococcus aureus (strain COL) | |
2 | A | (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | non-polymer | 368.4 | 1 | Chemie (1S7) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | water | water | 18.0 | 242 | Chemie (HOH) |
Sequence modifications
A: 21 - 383 (UniProt: A0A0H2WY27)
PDB | External Database | Details |
---|---|---|
Gly 17 | - | expression tag |
Ser 18 | - | expression tag |
His 19 | - | expression tag |
Met 20 | - | expression tag |
Leu 200 | Arg 200 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 41054.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 618.0 | |
All* | Total formula weight | 41672.3 |