7KC0
Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (P) | DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3') | polymer | 25 | 7682.0 | 1 | Saccharomyces cerevisiae | ||
| 2 | B (T) | DNA (25-MER) | polymer | 38 | 11677.5 | 1 | Saccharomyces cerevisiae | ||
| 3 | C, G, H (F, E, G) | Proliferating cell nuclear antigen | polymer | 258 | 28944.1 | 3 | UniProt (A0A6B7JGY6) Pfam (PF00705) Pfam (PF02747) UniProt (by SIFTS) (P15873) | Saccharomyces cerevisiae (Baker's yeast) | |
| 4 | D (A) | DNA polymerase | polymer | 1097 | 124707.4 | 1 | UniProt (A0A6A5Q0V0) Pfam (PF24055) Pfam (PF03104) Pfam (PF00136) Pfam (PF14260) UniProt (by SIFTS) (P15436) | Saccharomyces cerevisiae (Baker's yeast) | |
| 5 | E (B) | POL31 isoform 1 | polymer | 487 | 55352.7 | 1 | UniProt (A0A6A5PTG9) Pfam (PF18018) Pfam (PF04042) UniProt (by SIFTS) (P46957) | Saccharomyces cerevisiae (Baker's yeast) | |
| 6 | F (C) | POL32 isoform 1 | polymer | 350 | 40377.7 | 1 | UniProt (A0A6A5PT00) UniProt (by SIFTS) (P47110) | Saccharomyces cerevisiae (Baker's yeast) | HLJ1_G0030030.mRNA.1.CDS.1,BJ4_G0029460.mRNA.1.CDS.1 |
| 7 | I, L (P, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 8 | J (A) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 9 | K (A) | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 466.2 | 1 | Chemie (D3T) | |||
| 10 | M (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A: 1 - 1097 (UniProt: A0A6A5Q0V0)
C: 8 - 350 (UniProt: A0A6A5PT00)
| PDB | External Database | Details |
|---|---|---|
| Met 86 | Ile 86 | conflict |
| Ser 321 | Asp 321 | conflict |
| Ser 323 | Glu 323 | conflict |
| Pro 367 | His 367 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Asp 2 | - | expression tag |
| Gln 3 | - | expression tag |
| Lys 4 | - | expression tag |
| Ala 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Tyr 7 | - | expression tag |
| Thr 223 | Ala 223 | conflict |
| Gly 228 | Glu 228 | conflict |
| Ser 274 | Pro 274 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 326629.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 931.8 | |
| All* | Total formula weight | 327561.3 |
