7KBT
Factor VIII in complex with the anti-C2 domain antibody, G99
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor VIII,Coagulation factor VIII,Coagulation factor VIII,Coagulation factor VIII,Coagulation factor VIII | polymer | 1467 | 168287.0 | 1 | UniProt (P12263) UniProt (P00451) Pfam (PF07732) Pfam (PF00394) Pfam (PF07731) Pfam (PF00754) | Sus scrofa (Pig) | Procoagulant component,Antihemophilic factor,AHF,Procoagulant component,Procoagulant component,Procoagulant component,Antihemophilic factor,AHF,Procoagulant component |
| 2 | B (E) | G99 heavy chain | polymer | 224 | 23952.6 | 1 | Mus musculus | ||
| 3 | C (F) | G99 light chain | polymer | 214 | 23640.0 | 1 | Mus musculus | ||
| 4 | D, E (G, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | G (A) | COPPER (II) ION | non-polymer | 63.5 | 1 | Chemie (CU) | |||
| 7 | H (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 8 | I (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
A: -18 - 367 (UniProt: P12263)
A: 368 - 1626 (UniProt: P00451)
A: 1627 - 1636 (UniProt: P12263)
A: 1637 - 2019 (UniProt: P12263)
A: 2020 - 2332 (UniProt: P00451)
A: 368 - 1626 (UniProt: P00451)
A: 1627 - 1636 (UniProt: P12263)
A: 1637 - 2019 (UniProt: P12263)
A: 2020 - 2332 (UniProt: P00451)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 215879.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 390.2 | |
| All* | Total formula weight | 217118.7 |
