7K8G
Crystal structure of bovine RPE65 in complex with 4-fluoro-MB-004 and palmitate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Retinoid isomerohydrolase | polymer | 533 | 60935.0 | 2 | UniProt (Q28175) Pfam (PF03055) In PDB | Bos taurus (Bovine) | All-trans-retinyl-palmitate hydrolase,Retinal pigment epithelium-specific 65 kDa protein,Retinol isomerase |
| 2 | A, B | FE (II) ION | non-polymer | 55.8 | 2 | Chemie (FE2) | |||
| 3 | A, B | PALMITIC ACID | non-polymer | 256.4 | 2 | Chemie (PLM) | |||
| 4 | A, B | (1R)-3-amino-1-{4-fluoro-3-[(2-propylpentyl)oxy]phenyl}propan-1-ol | non-polymer | 297.4 | 2 | Chemie (W9A) | |||
| 5 | water | water | 18.0 | 851 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 533 (UniProt: Q28175)
| PDB | External Database | Details |
|---|---|---|
| Ace 1 | - | acetylation |
| Leu 341 | Ser 341 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 121870.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1219.4 | |
| All* | Total formula weight | 123089.4 |
