7K72
Structure of DNA ligase A from Mycobacterium tuberculosis bound to NAD
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | DNA ligase A | polymer | 336 | 37810.2 | 4 | UniProt (P9WNV1) Pfam (PF22745) Pfam (PF01653) In PDB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | LigA,Polydeoxyribonucleotide synthase [NAD(+)] |
2 | A, B, C, D | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 9 | Chemie (MG) | |||
4 | A, B | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
5 | A, B, C, D | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 5 | Chemie (MPD) | |||
6 | water | water | 18.0 | 807 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 328 (UniProt: P9WNV1)
PDB | External Database | Details |
---|---|---|
Met -7 | - | initiating methionine |
Ala -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 151240.6 | |
Non-Polymers* | Number of molecules | 20 |
Total formula weight | 3543.5 | |
All* | Total formula weight | 154784.1 |