7K72

Structure of DNA ligase A from Mycobacterium tuberculosis bound to NAD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003911	molecular_function	DNA ligase (NAD+) activity
B	0003911	molecular_function	DNA ligase (NAD+) activity
C	0003911	molecular_function	DNA ligase (NAD+) activity
D	0003911	molecular_function	DNA ligase (NAD+) activity

Functional Information from PROSITE/UniProt

site_id	PS01055
Number of Residues	30
Details	DNA_LIGASE_N1 NAD-dependent DNA ligase signature 1. KIDGVAlslvYreGrLtrasTRGDGrtGED

Chain	Residue	Details
A	LYS123-ASP152

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: N6-AMP-lysine intermediate => ECO:0000255|HAMAP-Rule:MF_01588

Chain	Residue	Details
A	LYS123
B	LYS123
C	LYS123
D	LYS123

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01588

Chain	Residue	Details
A	ASP41
D	ASP41
D	GLU121
D	LYS324
A	GLU121
A	LYS324
B	ASP41
B	GLU121
B	LYS324
C	ASP41
C	GLU121
C	LYS324

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site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01588, ECO:0000305|PubMed:15901723

Chain	Residue	Details
A	SER91
C	ARG144
C	GLU184
C	LYS300
D	SER91
D	ARG144
D	GLU184
D	LYS300
A	ARG144
A	GLU184
A	LYS300
B	SER91
B	ARG144
B	GLU184
B	LYS300
C	SER91

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