7K5B

Structure of outer-arm dynein bound to microtubule doublet in microtubule binding state 2 (MTBS-2)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Dynein heavy chain, outer arm protein	polymer	4615	533780.2	1	UniProt (Q22A67) Pfam (PF08385) Pfam (PF03028) Pfam (PF18198) Pfam (PF18199) Pfam (PF08393) Pfam (PF12774) Pfam (PF17852) Pfam (PF12775) Pfam (PF17857) Pfam (PF12780) Pfam (PF12777) Pfam (PF12781)	Tetrahymena thermophila
2	B (B)	Outer arm dynein beta heavy chain	polymer	4588	529207.2	1	UniProt (I7M9J2) Pfam (PF08385) Pfam (PF08393) Pfam (PF12774) Pfam (PF17852) Pfam (PF12775) Pfam (PF17857) Pfam (PF12780) Pfam (PF12777) Pfam (PF12781) Pfam (PF03028) Pfam (PF18198) Pfam (PF18199)	Tetrahymena thermophila
3	C (C)	gamma heavy chain	polymer	3947	450623.2	1	Pfam (PF08393) Pfam (PF12774) Pfam (PF17852) Pfam (PF12775) Pfam (PF17857) Pfam (PF12780) Pfam (PF12777) Pfam (PF12781) Pfam (PF03028) Pfam (PF18198) Pfam (PF18199) UniProt (by SIFTS) (Q22A67)	Tetrahymena thermophila
4	D (D)	Dynein intermediate chain 2	polymer	595	69514.8	1	UniProt (I7M008) Pfam (PF00400)	Tetrahymena thermophila
5	E (E)	Flagellar outer dynein arm intermediate protein, putative	polymer	557	63702.6	1	UniProt (Q23FU1)	Tetrahymena thermophila
6	F (F)	Dynein light chain roadblock-type 2 protein	polymer	128	14193.2	1	UniProt (I7MHB1) Pfam (PF03259)	Tetrahymena thermophila
7	G (G)	Dynein light chain roadblock-type 2 protein	polymer	151	17470.1	1	UniProt (Q22MV2) Pfam (PF03259)	Tetrahymena thermophila
8	H (H)	Dynein light chain	polymer	91	10649.2	1	UniProt (Q1HFW2) Pfam (PF01221)	Tetrahymena thermophila
9	I (I)	Dynein light chain	polymer	106	11830.5	1	UniProt (Q1HFX0) Pfam (PF01221)	Tetrahymena thermophila
10	J (J)	Dynein light chain	polymer	95	11435.1	1	UniProt (Q22R86) Pfam (PF01221)	Tetrahymena thermophila
11	K (K)	Dynein light chain	polymer	90	10670.1	1	UniProt (Q1HFV9) Pfam (PF01221)	Tetrahymena thermophila
12	L (L)	Dynein light chain	polymer	111	12516.5	1	UniProt (W7XJB1) Pfam (PF01221)	Tetrahymena thermophila
13	M (M)	Dynein light chain	polymer	87	10453.2	1	UniProt (Q1HFW0) Pfam (PF01221)	Tetrahymena thermophila
14	N (N)	Dynein light chain tctex-type 1 protein	polymer	114	12856.5	1	UniProt (A4VEB3) Pfam (PF03645)	Tetrahymena thermophila
15	O (O)	Dynein light chain 2A	polymer	120	14117.3	1	UniProt (Q1HGH8) Pfam (PF03645)	Tetrahymena thermophila
16	P (P)	Thioredoxin	polymer	112	12987.9	1	UniProt (A4VD75) Pfam (PF00085)	Tetrahymena thermophila
17	Q (Q)	Dynein light chain 1	polymer	192	21705.3	1	UniProt (Q1HGH9) Pfam (PF12799)	Tetrahymena thermophila
18	R (R)	Dynein light chain 4A	polymer	150	16803.7	1	UniProt (Q1HFX4) Pfam (PF13499) Pfam (PF00036)	Tetrahymena thermophila
19	BA, DA, IA, JA, S... (B, C, A)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	6	Chemie (ADP)
20	CA, EA, T (B, C, A)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	3	Chemie (ATP)
21	AA, FA, GA, HA, V... (B, C, A)	MAGNESIUM ION	non-polymer		24.3	9	Chemie (MG)

Sequence modifications

A: 5 - 4619 (UniProt: Q22A67)

PDB	External Database	Details
Asn 3238	Asp 3238	conflict

B: 1 - 4588 (UniProt: I7M9J2)

PDB	External Database	Details
Ala 36	Gln 36	conflict
Ala 1287	Leu 1287	conflict
Ala 3977	Ser 3977	conflict

N: 4 - 117 (UniProt: A4VEB3)

PDB	External Database	Details
Ala 92	Asn 92	conflict

Q: 2 - 193 (UniProt: Q1HGH9)

PDB	External Database	Details
Ala 2	Ser 2	conflict
Met 179	Tyr 179	conflict

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	1824516.5
Non-Polymers*	Number of molecules	18
	Total formula weight	4303.5
All*	Total formula weight	1828819.9

*Water molecules are not included.