7K5B

Structure of outer-arm dynein bound to microtubule doublet in microtubule binding state 2 (MTBS-2)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0005858	cellular_component	axonemal dynein complex
A	0005929	cellular_component	cilium
A	0005930	cellular_component	axoneme
A	0007018	biological_process	microtubule-based movement
A	0008569	molecular_function	minus-end-directed microtubule motor activity
A	0030286	cellular_component	dynein complex
A	0045505	molecular_function	dynein intermediate chain binding
A	0051959	molecular_function	dynein light intermediate chain binding
B	0003777	molecular_function	microtubule motor activity
B	0005524	molecular_function	ATP binding
B	0005930	cellular_component	axoneme
B	0007018	biological_process	microtubule-based movement
B	0008017	molecular_function	microtubule binding
B	0008569	molecular_function	minus-end-directed microtubule motor activity
B	0030286	cellular_component	dynein complex
B	0036156	cellular_component	inner dynein arm
B	0036159	biological_process	inner dynein arm assembly
B	0045505	molecular_function	dynein intermediate chain binding
B	0051959	molecular_function	dynein light intermediate chain binding
B	0060294	biological_process	cilium movement involved in cell motility
C	0005524	molecular_function	ATP binding
C	0007018	biological_process	microtubule-based movement
C	0008569	molecular_function	minus-end-directed microtubule motor activity
C	0030286	cellular_component	dynein complex
C	0045505	molecular_function	dynein intermediate chain binding
C	0051959	molecular_function	dynein light intermediate chain binding
H	0005856	cellular_component	cytoskeleton
H	0005868	cellular_component	cytoplasmic dynein complex
H	0007017	biological_process	microtubule-based process
H	0030286	cellular_component	dynein complex
H	0045505	molecular_function	dynein intermediate chain binding
I	0005856	cellular_component	cytoskeleton
I	0005868	cellular_component	cytoplasmic dynein complex
I	0007017	biological_process	microtubule-based process
I	0030286	cellular_component	dynein complex
I	0045505	molecular_function	dynein intermediate chain binding
J	0007017	biological_process	microtubule-based process
J	0030286	cellular_component	dynein complex
K	0005856	cellular_component	cytoskeleton
K	0005868	cellular_component	cytoplasmic dynein complex
K	0007017	biological_process	microtubule-based process
K	0030286	cellular_component	dynein complex
K	0045505	molecular_function	dynein intermediate chain binding
L	0007017	biological_process	microtubule-based process
L	0030286	cellular_component	dynein complex
M	0005856	cellular_component	cytoskeleton
M	0005868	cellular_component	cytoplasmic dynein complex
M	0007017	biological_process	microtubule-based process
M	0030286	cellular_component	dynein complex
M	0045505	molecular_function	dynein intermediate chain binding
N	0005737	cellular_component	cytoplasm
N	0005868	cellular_component	cytoplasmic dynein complex
N	0007018	biological_process	microtubule-based movement
N	0045505	molecular_function	dynein intermediate chain binding
O	0005737	cellular_component	cytoplasm
O	0005868	cellular_component	cytoplasmic dynein complex
O	0007018	biological_process	microtubule-based movement
O	0045505	molecular_function	dynein intermediate chain binding
P	0005737	cellular_component	cytoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005930	cellular_component	axoneme
R	0005509	molecular_function	calcium ion binding
R	0005856	cellular_component	cytoskeleton
R	0016460	cellular_component	myosin II complex
R	0043226	cellular_component	organelle

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DKDGSGEIEyeEF

Chain	Residue	Details
R	ASP135-PHE147

---

site_id	PS00213
Number of Residues	13
Details	LIPOCALIN Lipocalin signature. DFRs.RYHGTWHCI

Chain	Residue	Details
H	ASP48-ILE60

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FGCQAVH

Chain	Residue	Details
J	PHE84-HIS90

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. IGGGcyNgLLAVWDG

Chain	Residue	Details
E	ILE231-GLY245

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	356
Details	Coiled coil: {"evidences":[{"source":"PubMed","id":"33632841","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ZYW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33632841","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ZYW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ZYY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	13
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33632841","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ZYY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	105
Details	Repeat: {"description":"WD 1","evidences":[{"source":"PubMed","id":"33632841","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ZYW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	87
Details	Repeat: {"description":"WD 2","evidences":[{"source":"PubMed","id":"33632841","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ZYW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	78
Details	Repeat: {"description":"WD 4","evidences":[{"source":"PubMed","id":"33632841","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ZYW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	93
Details	Repeat: {"description":"WD 5","evidences":[{"source":"PubMed","id":"33632841","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ZYW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	85
Details	Repeat: {"description":"WD 6","evidences":[{"source":"PubMed","id":"33632841","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ZYW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	79
Details	Repeat: {"description":"WD 7","evidences":[{"source":"PubMed","id":"33632841","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ZYW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	38
Details	Repeat: {"description":"WD 3","evidences":[{"source":"PubMed","id":"33632841","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ZYW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---