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7K2U

DHODH IN COMPLEX WITH LIGAND 13

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydroorotate dehydrogenase (quinone), mitochondrialpolymer36939984.71UniProt (Q02127)
Pfam (PF01180)
Homo sapiens (Human)DHOdehase,Dihydroorotate oxidase
2B
(A)
FLAVIN MONONUCLEOTIDEnon-polymer456.31Chemie (FMN)
3C
(A)
OROTIC ACIDnon-polymer156.11Chemie (ORO)
4D
(A)
6-fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-N-methoxy-3-methylquinoline-4-carboxamidenon-polymer404.41Chemie (VU7)
5E, F, I, J
(A)
ACETATE IONnon-polymer59.04Chemie (ACT)
6G, K, L, O
(A)
SULFATE IONnon-polymer96.14Chemie (SO4)
7H, N
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
8M
(A)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
9P
(A)
waterwater18.0263Chemie (HOH)
Sequence modifications
A: 30 - 396 (UniProt: Q02127)
PDBExternal DatabaseDetails
Gly 28-expression tag
Ala 29-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39984.7
Non-Polymers*Number of molecules14
Total formula weight1971.6
All*Total formula weight41956.3
*Water molecules are not included.

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PDB entries from 2025-12-17

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