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7K0O

Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 3

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, E)
Serine palmitoyltransferase 1polymer47352806.82UniProt (O15269)
Pfam (PF00155)
Homo sapiens (human)Long chain base biosynthesis protein 1,LCB 1,Serine-palmitoyl-CoA transferase 1,SPT1
2B, H
(B, F)
Serine palmitoyltransferase 2polymer54461080.02UniProt (O15270)
Pfam (PF00155)
Homo sapiens (human)Long chain base biosynthesis protein 2,LCB 2,Long chain base biosynthesis protein 2a,LCB2a,Serine-palmitoyl-CoA transferase 2,SPT 2
3C, F
(C, G)
Serine palmitoyltransferase small subunit Apolymer718471.12UniProt (Q969W0)
Pfam (PF11779)
Homo sapiens (human)Small subunit of serine palmitoyltransferase A,ssSPTa
4D, G
(D, H)
ORM1-like protein 3polymer15317512.62UniProt (Q8N138)
Pfam (PF04061)
Homo sapiens (human)
5I, J, K, L, M...
(B, C, D, G, H...)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.112Chemie (POV)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight279741.0
Non-Polymers*Number of molecules12
Total formula weight9120.9
All*Total formula weight288861.9
*Water molecules are not included.

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PDB entries from 2025-07-16

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