7JX1
E. coli TSase complex with a bi-substrate reaction intermediate analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thymidylate synthase | polymer | 264 | 30559.7 | 2 | UniProt (A0A029ILG4) Pfam (PF00303) UniProt (by SIFTS) (P0A884) | Escherichia coli | TSase |
| 2 | C (A) | N-(4-{[(2,4-diamino-7,8-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]amino}benzene-1-carbonyl)-L-glutamic acid | non-polymer | 441.4 | 1 | Chemie (VLA) PubChem (155923772) | |||
| 3 | D (A) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 1 | Chemie (TMP) PubChem (1139) PubChem (444919) PubChem (5748250) PubChem (10147784) PubChem (18531120) PubChem (20711568) PubChem (23657880) PubChem (24802545) PubChem (44361457) PubChem (25113134) PubChem (9700) PubChem (51397487) PubChem (5274091) PubChem (129069890) PubChem (133126478) PubChem (164603144) | |||
| 4 | E (B) | (2S)-2-({4-[({(6R)-2,4-diamino-5-[(1-{(2R,4S,5R)-4-hydroxy-5-[(phosphonooxy)methyl]tetrahydrofuran-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl}methyl)amino]benzoyl}amino)pentanedioic acid (non-preferred name) | non-polymer | 763.6 | 1 | Chemie (VLD) | |||
| 5 | F (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61119.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1622.3 | |
| All* | Total formula weight | 62741.6 |
