7JX1
E. coli TSase complex with a bi-substrate reaction intermediate analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thymidylate synthase | polymer | 264 | 30559.7 | 2 | UniProt (A0A029ILG4) Pfam (PF00303) UniProt (by SIFTS) (P0A884) | Escherichia coli | TSase |
| 2 | C (A) | N-(4-{[(2,4-diamino-7,8-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]amino}benzene-1-carbonyl)-L-glutamic acid | non-polymer | 441.4 | 1 | Chemie (VLA) | |||
| 3 | D (A) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 1 | Chemie (TMP) | |||
| 4 | E (B) | (2S)-2-({4-[({(6R)-2,4-diamino-5-[(1-{(2R,4S,5R)-4-hydroxy-5-[(phosphonooxy)methyl]tetrahydrofuran-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl}methyl)amino]benzoyl}amino)pentanedioic acid (non-preferred name) | non-polymer | 763.6 | 1 | Chemie (VLD) | |||
| 5 | F (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61119.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1622.3 | |
| All* | Total formula weight | 62741.6 |
