7JVX
Crystal structure of PTEN (aa 7-353 followed by spacer TGGGSGGTGGGSGGTGGGCY ligated to peptide pSDpTpTDpSDPENEPFDED)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | polymer | 422 | 48555.5 | 1 | UniProt (P60484) Pfam (PF22785) Pfam (PF10409) | Homo sapiens (Human) | Mutated in multiple advanced cancers 1,Phosphatase and tensin homolog |
| 2 | B, C (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) |
Sequence modifications
A: 1 - 422 (UniProt: P60484)
| PDB | External Database | Details |
|---|---|---|
| Thr 381 | - | insertion |
| Gly 382 | - | insertion |
| Gly 383 | - | insertion |
| Gly 384 | - | insertion |
| Ser 385 | - | insertion |
| Gly 386 | - | insertion |
| Gly 387 | - | insertion |
| Thr 388 | - | insertion |
| Gly 389 | - | insertion |
| Gly 390 | - | insertion |
| Gly 391 | - | insertion |
| Ser 392 | - | insertion |
| Gly 393 | - | insertion |
| Gly 394 | - | insertion |
| Thr 395 | - | insertion |
| Gly 396 | - | insertion |
| Gly 397 | - | insertion |
| Gly 398 | - | insertion |
| Cys 399 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 48555.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 189.9 | |
| All* | Total formula weight | 48745.4 |
