7JVN
Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor Compound 24
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosine-protein phosphatase non-receptor type 11 | polymer | 525 | 60248.0 | 2 | UniProt (Q06124) Pfam (PF00017) Pfam (PF00102) | Homo sapiens (Human) | Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,Shp2,SH-PTP3 |
| 2 | C, H (A, B) | 6-(4-amino-4-methylpiperidin-1-yl)-3-[(2,3-dichlorophenyl)sulfanyl]pyrazin-2-amine | non-polymer | 384.3 | 2 | Chemie (VKP) | |||
| 3 | D, E, F, G, I... (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 7 | Chemie (PO4) | |||
| 4 | L, M (A, B) | water | water | 18.0 | 738 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120495.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1433.5 | |
| All* | Total formula weight | 121929.4 |
