Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue VKP A 601 |
| Chain | Residue |
| A | ARG111 |
| A | LYS492 |
| A | HOH712 |
| A | PHE113 |
| A | THR218 |
| A | THR219 |
| A | GLU249 |
| A | GLU250 |
| A | THR253 |
| A | LEU254 |
| A | PRO491 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 602 |
| Chain | Residue |
| A | ARG32 |
| A | SER34 |
| A | THR42 |
| A | HOH784 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 603 |
| Chain | Residue |
| A | PHE346 |
| A | ASN349 |
| A | ARG413 |
| A | HOH724 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 604 |
| Chain | Residue |
| A | LYS131 |
| A | ASN217 |
| A | ARG220 |
| A | HOH702 |
| A | HOH704 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue PO4 A 605 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residue VKP B 601 |
| Chain | Residue |
| B | ARG111 |
| B | PHE113 |
| B | HIS114 |
| B | THR218 |
| B | THR219 |
| B | GLU249 |
| B | GLU250 |
| B | THR253 |
| B | LEU254 |
| B | GLN257 |
| B | PRO491 |
| B | LYS492 |
| B | HOH720 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 B 602 |
| Chain | Residue |
| B | ARG32 |
| B | SER34 |
| B | LYS35 |
| B | SER36 |
| B | THR42 |
| B | HOH709 |
| B | HOH808 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 B 603 |
| Chain | Residue |
| B | PHE346 |
| B | GLN347 |
| B | ASN349 |
| B | ARG413 |
| B | HOH726 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue PO4 B 604 |
| Chain | Residue |
| B | ARG138 |
| B | MET171 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGigRTG |
| Chain | Residue | Details |
| A | VAL457-GLY467 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Phosphocysteine intermediate |
| Chain | Residue | Details |
| A | CYS459 | |
| B | CYS459 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| B | CYS459 | |
| B | GLN506 | |
| A | ASP425 | |
| A | CYS459 | |
| A | GLN506 | |
| B | ASP425 | |
| Chain | Residue | Details |
| A | THR2 | |
| B | THR2 | |
| Chain | Residue | Details |
| B | TYR62 | |
| A | TYR62 | |
| Chain | Residue | Details |
| A | TYR66 | |
| B | TYR66 | |
