7JQC
SARS-CoV-2 Nsp1, CrPV IRES and rabbit 40S ribosome complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | rRNA | polymer | 1869 | 602777.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
2 | a | eS25 | polymer | 125 | 13776.2 | 1 | UniProt (G1TDB3) Pfam (PF03297) In PDB | Oryctolagus cuniculus (Rabbit) | |
3 | B | 40S ribosomal protein SA | polymer | 295 | 32958.0 | 1 | UniProt (G1TLT8) Pfam (PF00318) Pfam (PF16122) In PDB | Oryctolagus cuniculus (Rabbit) | 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40 |
4 | b | 40S ribosomal protein S26 | polymer | 115 | 13047.5 | 1 | UniProt (G1TFE8) Pfam (PF01283) In PDB | Oryctolagus cuniculus (Rabbit) | |
5 | C | eS1 | polymer | 264 | 30002.1 | 1 | UniProt (G1SS70) Pfam (PF01015) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S3a |
6 | D | uS5 | polymer | 293 | 31327.4 | 1 | Pfam (PF00333) Pfam (PF03719) UniProt (by SIFTS) (P15880) In PDB | Oryctolagus cuniculus (Rabbit) | |
7 | d | eS28 | polymer | 69 | 7855.1 | 1 | UniProt (G1TIB4) Pfam (PF01200) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S28 |
8 | E | Ribosomal protein S3 | polymer | 243 | 26715.3 | 1 | UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189) In PDB | Oryctolagus cuniculus (Rabbit) | |
9 | f | eS30 | polymer | 133 | 14498.9 | 1 | UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S30 |
10 | G | uS7 | polymer | 204 | 22913.5 | 1 | UniProt (G1TFM5) Pfam (PF00177) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S5 |
11 | g | eS31 | polymer | 156 | 18004.0 | 1 | UniProt (G1SK22) Pfam (PF00240) Pfam (PF01599) UniProt (by SIFTS) (P62979) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S27a |
12 | H | eS6 | polymer | 249 | 28751.9 | 1 | UniProt (G1TM55) Pfam (PF01092) UniProt (by SIFTS) (A0A5K1UJS7) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S6 |
13 | h | RACK1 | polymer | 317 | 35115.7 | 1 | UniProt (G1SJB4) Pfam (PF00400) In PDB | Oryctolagus cuniculus (Rabbit) | |
14 | I | eS7 | polymer | 194 | 22168.9 | 1 | UniProt (G1SVB0) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S7 |
15 | J | eS8 | polymer | 208 | 24263.4 | 1 | UniProt (G1TJW1) Pfam (PF01201) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S8 |
16 | K | uS4 | polymer | 194 | 22641.6 | 1 | UniProt (B7NZS8) Pfam (PF00163) Pfam (PF01479) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S9 |
17 | L | S10_plectin domain-containing protein | polymer | 165 | 18933.8 | 1 | UniProt (G1TPV3) Pfam (PF03501) In PDB | Oryctolagus cuniculus (Rabbit) | |
18 | N | eS12 | polymer | 132 | 14539.0 | 1 | UniProt (G1SFR8) Pfam (PF01248) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S12 |
19 | Q | uS19 | polymer | 145 | 17049.2 | 1 | UniProt (G1U0Q2) Pfam (PF00203) In PDB | Oryctolagus cuniculus (Rabbit) | |
20 | R | Uncharacterized protein | polymer | 146 | 16477.4 | 1 | UniProt (G1SGX4) Pfam (PF00380) In PDB | Oryctolagus cuniculus (Rabbit) | |
21 | S | eS17 | polymer | 135 | 15552.1 | 1 | UniProt (G1TU13) Pfam (PF00833) In PDB | Oryctolagus cuniculus (Rabbit) | |
22 | T | uS13 | polymer | 152 | 17759.8 | 1 | UniProt (G1TPG3) Pfam (PF00416) In PDB | Oryctolagus cuniculus (Rabbit) | |
23 | U | Uncharacterized protein | polymer | 145 | 16106.6 | 1 | UniProt (G1TN62) Pfam (PF01090) In PDB | Oryctolagus cuniculus (Rabbit) | |
24 | V | uS10 | polymer | 119 | 13398.8 | 1 | UniProt (G1SIZ2) Pfam (PF00338) In PDB | Oryctolagus cuniculus (Rabbit) | |
25 | W | 40S ribosomal protein S21 | polymer | 83 | 9124.4 | 1 | UniProt (G1TM82) Pfam (PF01249) UniProt (by SIFTS) (P63220) In PDB | Oryctolagus cuniculus (Rabbit) | |
26 | Z | 40S ribosomal protein S24 | polymer | 130 | 15107.9 | 1 | UniProt (A0A5F9CBF4) Pfam (PF01282) UniProt (by SIFTS) (G1T3D8) In PDB | Oryctolagus cuniculus (Rabbit) | |
27 | F | Host translation inhibitor nsp1 | polymer | 36 | 4100.4 | 1 | UniProt (P0DTD1) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | Leader protein,Non-structural protein 1,nsp1 |
28 | i | Cricket paralysis virus IRES RNA | polymer | 192 | 61462.2 | 1 | GenBank (8895506) | Cricket paralysis virus | |
29 | M | 40S ribosomal protein S4 | polymer | 263 | 29658.9 | 1 | UniProt (G1TK17) Pfam (PF08071) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) In PDB | Oryctolagus cuniculus (Rabbit) | |
30 | O | uS17 | polymer | 158 | 18468.8 | 1 | UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S11 |
31 | P | uS15 | polymer | 151 | 17259.4 | 1 | UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312) UniProt (by SIFTS) (P62277) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S13 |
32 | X | Uncharacterized protein | polymer | 168 | 18134.0 | 1 | UniProt (G1U472) Pfam (PF00411) UniProt (by SIFTS) (G1T1F0) In PDB | Oryctolagus cuniculus (Rabbit) | |
33 | Y | uS8 | polymer | 130 | 14865.6 | 1 | UniProt (G1TG89) Pfam (PF00410) In PDB | Oryctolagus cuniculus (Rabbit) | Ribosomal protein S15a |
34 | c | Uncharacterized protein | polymer | 143 | 15844.7 | 1 | UniProt (G1SZ47) Pfam (PF00164) In PDB | Oryctolagus cuniculus (Rabbit) | |
35 | e | eS27 | polymer | 84 | 9480.2 | 1 | UniProt (G1TZ76) Pfam (PF01667) In PDB | Oryctolagus cuniculus (Rabbit) | 40S ribosomal protein S27 |
Sequence modifications
B: 1 - 295 (UniProt: G1TLT8)
b: 1 - 115 (UniProt: G1TFE8)
J: 1 - 208 (UniProt: G1TJW1)
U: 1 - 145 (UniProt: G1TN62)
W: 1 - 83 (UniProt: G1TM82)
i: 6030 - 6221 (GenBank: 8895506)
PDB | External Database | Details |
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Thr 114 | Ala 114 | conflict |
PDB | External Database | Details |
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Arg 28 | Cys 28 | conflict |
Ala 56 | Val 56 | conflict |
Arg 109 | Pro 109 | conflict |
PDB | External Database | Details |
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Arg 47 | Gly 47 | conflict |
PDB | External Database | Details |
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Gly 119 | Trp 119 | conflict |
PDB | External Database | Details |
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Asn 3 | Ser 3 | conflict |
Asp 4 | Asn 4 | conflict |
Gln 33 | Pro 33 | conflict |
Phe 50 | Ser 50 | conflict |
Ala 75 | Ser 75 | conflict |
Asp 76 | His 76 | conflict |
Lys 81 | Gln 81 | conflict |
PDB | External Database | Details |
---|---|---|
C 6176 | U 6176 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 35 |
Total formula weight | 1290140.4 | |
All* | Total formula weight | 1290140.4 |