7JOA
2:1 cGAS-nucleosome complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.2 | polymer | 136 | 15421.1 | 2 | UniProt (Q71DI3) Pfam (PF00125) | Homo sapiens (Human) | H3-clustered histone 13,H3-clustered histone 14,H3-clustered histone 15,Histone H3/m,Histone H3/o |
| 2 | B, F (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (Human) | |
| 3 | C, G (C, G) | Histone H2A type 1 | polymer | 129 | 13990.3 | 2 | UniProt (P0C0S8) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (Human) | H2A.1,Histone H2A/ptl |
| 4 | D, H (D, H) | Histone H2B type 1-C/E/F/G/I | polymer | 125 | 13806.0 | 2 | UniProt (P62807) Pfam (PF00125) | Homo sapiens (Human) | Histone H2B.1 A,Histone H2B.a,H2B/a,Histone H2B.g,H2B/g,Histone H2B.h,H2B/h,Histone H2B.k,H2B/k,Histone H2B.l,H2B/l |
| 5 | I (I) | DNA (145-MER) | polymer | 147 | 45610.0 | 1 | synthetic construct | ||
| 6 | J (J) | DNA (145-MER) | polymer | 147 | 45138.8 | 1 | synthetic construct | ||
| 7 | K (K) | Cyclic GMP-AMP synthase | polymer | 366 | 42984.7 | 1 | UniProt (Q8C6L5) Pfam (PF03281) Pfam (PF20266) | Mus musculus (Mouse) | m-cGAS,2'3'-cGAMP synthase,Mab-21 domain-containing protein 1 |
| 8 | L (K) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 242957.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 243022.7 |
