7JMT

Crystal structure of schistosome BCL-2 bound to ABT-737

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	BCL-2 protein	polymer	210	23416.7	6	UniProt (Q5BWX6) Pfam (PF00452) UniProt (by SIFTS) (A0A4Z2CSJ3)	Schistosoma japonicum (Blood fluke)
2	G, H, I, J, K... (A, B, C, D, E...)	4-{4-[(4'-CHLOROBIPHENYL-2-YL)METHYL]PIPERAZIN-1-YL}-N-{[4-({(1R)-3-(DIMETHYLAMINO)-1-[(PHENYLTHIO)METHYL]PROPYL}AMINO)-3-NITROPHENYL]SULFONYL}BENZAMIDE	non-polymer		813.4	6	Chemie (N3C)
3	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	32	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	140499.9
Non-Polymers*	Number of molecules	6
	Total formula weight	4880.6
All*	Total formula weight	145380.5

*Water molecules are not included.