7JMT

Crystal structure of schistosome BCL-2 bound to ABT-737

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0042981	biological_process	regulation of apoptotic process
B	0042981	biological_process	regulation of apoptotic process
C	0042981	biological_process	regulation of apoptotic process
D	0042981	biological_process	regulation of apoptotic process
E	0042981	biological_process	regulation of apoptotic process
F	0042981	biological_process	regulation of apoptotic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue N3C A 1001

Chain	Residue
A	LEU58
A	PHE166
A	PHE62
A	PHE66
A	LEU103
A	ASN108
A	GLY110
A	ARG111
A	ALA114
A	ILE121

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site_id	AC2
Number of Residues	9
Details	binding site for residue N3C B 1001

Chain	Residue
B	ASP61
B	PHE62
B	PHE66
B	ILE99
B	ASN108
B	ALA114
B	ALA117
B	PHE118
B	PHE166

---

site_id	AC3
Number of Residues	11
Details	binding site for residue N3C C 1001

Chain	Residue
C	LEU58
C	PHE62
C	PHE66
C	GLN68
C	LEU103
C	ASN108
C	GLY110
C	ALA114
C	PHE118
C	ILE121
C	PHE166

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site_id	AC4
Number of Residues	13
Details	binding site for residue N3C D 1001

Chain	Residue
C	HIS70
C	GLU73
C	PRO74
D	LEU58
D	PHE62
D	PHE66
D	ILE99
D	LEU103
D	ASN108
D	GLY110
D	ARG111
D	ALA114
D	PHE166

---

site_id	AC5
Number of Residues	10
Details	binding site for residue N3C E 1001

Chain	Residue
E	LEU58
E	PHE62
E	ARG65
E	PHE66
E	ILE99
E	ASN108
E	GLY110
E	ARG111
E	ALA114
E	PHE166

---

site_id	AC6
Number of Residues	13
Details	binding site for residue N3C F 1001

Chain	Residue
F	ASP61
F	PHE62
F	ARG65
F	PHE66
F	ILE99
F	LEU103
F	ASN108
F	GLY110
F	ARG111
F	ALA114
F	PHE118
F	ILE121
F	PHE166

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