7JL8
Human PrimPol extending from the correct primer base C opposite the 8-oxoguanine lesion
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | DNA-directed primase/polymerase protein | polymer | 354 | 41038.5 | 2 | UniProt (Q96LW4) Pfam (PF01896) | Homo sapiens (Human) | hPrimpol1,Coiled-coil domain-containing protein 111 |
| 2 | B, E (C, G) | DNA (5'-D(P*AP*TP*(8OG)P*CP*CP*TP*AP*CP*CP*AP*CP*A)-3') | polymer | 17 | 5053.3 | 2 | synthetic construct | ||
| 3 | C, F (D, H) | DNA (5'-D(P*GP*TP*GP*GP*TP*AP*GP*GP*C)-3') | polymer | 13 | 4103.7 | 2 | synthetic construct | ||
| 4 | G, N (A, B) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 2 | Chemie (DTP) | |||
| 5 | H, O, P (A, B) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 6 | I, L, Q, R, S (A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 7 | J (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 8 | K, M, T (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 9 | U, V, W, X, Y (A, C, B, G, H) | water | water | 18.0 | 161 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 100390.8 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1943.5 | |
| All* | Total formula weight | 102334.3 |
