7JKZ
Bromodomain-containing protein 4 (BRD4) bromodomain 2 (BD2) complexed with YF3-126
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bromodomain-containing protein 4 | polymer | 130 | 15060.3 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
2 | A | N-(1-[1,1-di(pyridin-2-yl)ethyl]-6-{1-methyl-6-oxo-5-[(piperidin-4-yl)amino]-1,6-dihydropyridin-3-yl}-1H-indol-4-yl)ethanesulfonamide | non-polymer | 611.8 | 1 | Chemie (YF6) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A: 333 - 460 (UniProt: O60885)
PDB | External Database | Details |
---|---|---|
Ser 331 | - | expression tag |
Met 332 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 15060.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 765.9 | |
All* | Total formula weight | 15826.3 |