7JKZ
Bromodomain-containing protein 4 (BRD4) bromodomain 2 (BD2) complexed with YF3-126
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue YF6 A 501 |
| Chain | Residue |
| A | VAL350 |
| A | ASP381 |
| A | LEU387 |
| A | LEU407 |
| A | TYR432 |
| A | ASN433 |
| A | GOL503 |
| A | HOH607 |
| A | HOH608 |
| A | HOH619 |
| A | HOH626 |
| A | LEU354 |
| A | LYS355 |
| A | TRP374 |
| A | PRO375 |
| A | PHE376 |
| A | LYS378 |
| A | PRO379 |
| A | VAL380 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | LYS367 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | LYS362 |
| A | LYS404 |
| A | GLU408 |
| A | HIS437 |
| A | YF6501 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Acetylated histone binding => ECO:0000269|PubMed:22464331 |
| Chain | Residue | Details |
| A | ASN433 |
