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7JJL

Crystal structure of Importin Alpha 3 in complex with human LSD1 NLS

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Importin subunit alpha-3polymer46551120.71UniProt (O00629)
Pfam (PF01749)
Pfam (PF16186)
Pfam (PF00514)
Homo sapiens (Human)Importin alpha Q1,Qip1,Karyopherin subunit alpha-4
2B
(B)
Lysine-specific histone demethylase 1Apolymer263144.51UniProt (O60341)Homo sapiens (Human)BRAF35-HDAC complex protein BHC110,Flavin-containing amine oxidase domain-containing protein 2,[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A
3C
(A)
waterwater18.01Chemie (HOH)
Sequence modifications
A: 64 - 521 (UniProt: O00629)
PDBExternal DatabaseDetails
Glu 57-expression tag
Asn 58-expression tag
Leu 59-expression tag
Tyr 60-expression tag
Phe 61-expression tag
Gln 62-expression tag
Ser 63-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight54265.2
All*Total formula weight54265.2
*Water molecules are not included.

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PDB entries from 2025-07-30

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