7JIS
HUMAN PI3KDELTA IN COMPLEX WITH COMPOUND 2F
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | polymer | 1018 | 116600.6 | 1 | UniProt (O00329) Pfam (PF02192) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) | Homo sapiens (Human) | PtdIns-3-kinase subunit delta,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,p110delta |
| 2 | B (B) | Phosphatidylinositol 3-kinase regulatory subunit alpha | polymer | 169 | 20879.6 | 1 | UniProt (P23727) Pfam (PF16454) | Bos taurus (Bovine) | PtdIns-3-kinase regulatory subunit alpha,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,PtdIns-3-kinase regulatory subunit p85-alpha |
| 3 | C (A) | (3S)-3-benzyl-5-[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]-3-methyl-1,3-dihydro-2H-indol-2-one | non-polymer | 475.5 | 1 | Chemie (VBS) | |||
| 4 | D (A) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 137480.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 475.5 | |
| All* | Total formula weight | 137955.7 |
