7JIS

HUMAN PI3KDELTA IN COMPLEX WITH COMPOUND 2F

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	polymer	1018	116600.6	1	UniProt (O00329) Pfam (PF02192) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB	Homo sapiens (Human)	PtdIns-3-kinase subunit delta,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,p110delta
2	B	Phosphatidylinositol 3-kinase regulatory subunit alpha	polymer	169	20879.6	1	UniProt (P23727) Pfam (PF16454) In PDB	Bos taurus (Bovine)	PtdIns-3-kinase regulatory subunit alpha,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,PtdIns-3-kinase regulatory subunit p85-alpha
3	A	(3S)-3-benzyl-5-[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]-3-methyl-1,3-dihydro-2H-indol-2-one	non-polymer		475.5	1	Chemie (VBS)
4		water	water		18.0	18	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	137480.2
Non-Polymers*	Number of molecules	1
	Total formula weight	475.5
All*	Total formula weight	137955.7

*Water molecules are not included.