7JHO
Structure of human beta 1,3-N-acetylglucosaminyltransferase 2 with UDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 | polymer | 370 | 43300.3 | 2 | UniProt (Q9NY97) Pfam (PF01762) In PDB | Homo sapiens (Human) | Beta-1,3-N-acetylglucosaminyltransferase 1,Beta3Gn-T1,3-galactosyltransferase 7,b3Gal-T7,Beta-3-Gx-T7,UDP-Gal:beta-GlcNAc beta-1,UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2,Beta3Gn-T2,UDP-galactose:beta-N-acetylglucosamine beta-1 |
| 2 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D, F | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 4 | E | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 1 | In PDB GlyTouCan (G82348BZ) | |||
| 5 | A, B | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
| 6 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 7 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 8 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 9 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 10 | water | water | 18.0 | 636 | Chemie (HOH) |
Sequence modifications
A, B: 45 - 397 (UniProt: Q9NY97)
| PDB | External Database | Details |
|---|---|---|
| Met 28 | - | initiating methionine |
| His 29 | - | expression tag |
| His 30 | - | expression tag |
| His 31 | - | expression tag |
| His 32 | - | expression tag |
| His 33 | - | expression tag |
| His 34 | - | expression tag |
| His 35 | - | expression tag |
| His 36 | - | expression tag |
| Glu 37 | - | expression tag |
| Asn 38 | - | expression tag |
| Leu 39 | - | expression tag |
| Tyr 40 | - | expression tag |
| Phe 41 | - | expression tag |
| Gln 42 | - | expression tag |
| Gly 43 | - | expression tag |
| Ser 44 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86600.5 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 3303.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1517.4 | |
| All* | Total formula weight | 91420.9 |
