7JHN
Structure of human beta 1,3-N-acetylglucosaminyltransferase 2 with UDP and trisaccharide GlcNAc-beta1-3Gal-beta1-4GlcNAc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 | polymer | 370 | 43300.3 | 1 | UniProt (Q9NY97) Pfam (PF01762) | Homo sapiens (Human) | Beta-1,3-N-acetylglucosaminyltransferase 1,Beta3Gn-T1,3-galactosyltransferase 7,b3Gal-T7,Beta-3-Gx-T7,UDP-Gal:beta-GlcNAc beta-1,UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2,Beta3Gn-T2,UDP-galactose:beta-N-acetylglucosamine beta-1 |
| 2 | B (B) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G29487JS) | |||
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 7 | G, H (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 8 | I (A) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A: 45 - 397 (UniProt: Q9NY97)
| PDB | External Database | Details |
|---|---|---|
| Met 28 | - | initiating methionine |
| His 29 | - | expression tag |
| His 30 | - | expression tag |
| His 31 | - | expression tag |
| His 32 | - | expression tag |
| His 33 | - | expression tag |
| His 34 | - | expression tag |
| His 35 | - | expression tag |
| His 36 | - | expression tag |
| Glu 37 | - | expression tag |
| Asn 38 | - | expression tag |
| Leu 39 | - | expression tag |
| Tyr 40 | - | expression tag |
| Phe 41 | - | expression tag |
| Gln 42 | - | expression tag |
| Gly 43 | - | expression tag |
| Ser 44 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43300.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1497.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 720.6 | |
| All* | Total formula weight | 45518.2 |
